The Hypancistrus zebra, also known as Zebra Plecos or L046, is a distinct species. Contrary to common belief, the zebra pleco is primarily a carnivore rather than an algae eater. Its small and lightly toothed mouth suggests a limited ability to consume algae effectively. As a result, it is recommended to provide a diet consisting mainly of meaty foods such as bloodworms, discus food, and brine shrimp.

While the zebra pleco is generally peaceful in nature, it is important to carefully select tankmates. This is because zebras may struggle to compete for food when housed with fast or aggressive tankmates. Ensuring compatible tankmates will help to maintain a harmonious environment for all inhabitants.